abstract：AIMS:To develop a risk "engine" or calculator, integrating the risks of hyperglycemia, maternal BMI and other basic demographic data commonly available at the time of the pregnancy oral glucose tolerance test (OGTT), to predict an individual's absolute risk of specific adverse pregnancy outcomes. METHODS:Data from the...

journal_title：Diabetes research and clinical practice

authors： McIntyre HD,Gibbons KS,Lowe J,Oats JJN

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:To examine whether QTc interval prolongation is an independent risk factor of outcomes in patients with diabetic foot ulcers (DFU). RESEARCH DESIGN AND METHODS:331 patients with type 2 diabetes and DFU hospitalized in a Chinese tertiary hospital were recruited. ECG was done at baseline and QTc interval was ...

journal_title：Diabetes research and clinical practice

authors： Wang S,He Y,Xu L,Zhang S,Gu X,Gu J,Shi J,Shen Y,Tang Z

更新日期：2018-04-01 00:00:00

abstract：AIMS:Our aim was to assess causes of death and temporal changes in excess mortality among patients with new-onset type 2 diabetes in Skaraborg, Sweden. METHODS:Patients from the Skaraborg Diabetes Register with prospectively registered new-onset type 2 diabetes 1991-2004 were included. Five individual controls matched...

journal_title：Diabetes research and clinical practice

authors： Andersson T,Hjerpe P,Carlsson AC,Pivodic A,Wändell P,Manhem K,Bengtsson Boström K

更新日期：2018-04-01 00:00:00

abstract：:The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to the development of many novel lipid-lowering drugs. Accumulating evidence sugge...

journal_title：Diabetes research and clinical practice

authors： Tsimihodimos V,Elisaf M

更新日期：2018-03-01 00:00:00

abstract：AIMS:To evaluate the long-term remission rates of type 2 diabetes mellitus and associated comorbidities after gastric bypass surgery in a complete cohort, in a real-life clinic setting. METHODS:A retrospective study of all consecutive patients with type 2 diabetes mellitus who underwent gastric bypass at a Veterans Af...

journal_title：Diabetes research and clinical practice

authors： Carranza-Leon BG,Puzziferri N,Adams-Huet B,Jabbour I,Lingvay I

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Increasing studies have focused on the relationship between soy intake and type 2 diabetes mellitus risk, but the results are inconsistent. We conduct a meta-analysis to evaluate the relationship. METHODS:The databases of PubMed, Web of Science and Embase were searched up to Dec 2016. A random-effect model ...

journal_title：Diabetes research and clinical practice

authors： Li W,Ruan W,Peng Y,Wang D

更新日期：2018-03-01 00:00:00

abstract：:Cardiovascular risk reduction in individuals with Type 2 diabetes mellitus (T2DM) is a key part of clinical management. Sodium-glucose co-transporter (SGLT2) inhibitors improve glycaemic control, reduce body weight and decrease blood pressure. In addition, the SGLT2 inhibitors empagliflozin and canagliflozin reduced t...

journal_title：Diabetes research and clinical practice

authors： d'Emden M,Amerena J,Deed G,Pollock C,Cooper ME

更新日期：2018-02-01 00:00:00

abstract：AIM:To investigate the association of type 2 diabetes mellitus (T2DM) risk and plasma lipid levels in rural Chinese. METHODS:Each lipid variable was divided into quartiles and dichotomized by clinical cutoff points. Cox proportional-hazards model was used to estimate hazard ratios (HRs) and 95% confidence intervals (C...

journal_title：Diabetes research and clinical practice

authors： Zhang M,Zhou J,Liu Y,Sun X,Luo X,Han C,Zhang L,Wang B,Ren Y,Zhao Y,Zhang D,Liu X,Hu D

更新日期：2018-01-01 00:00:00

abstract：:The relationship between depressive symptoms and glycemic control in youth with type 2 diabetes was assessed at baseline (n = 682), 6, and/or 24 months (n = 576). Neither baseline nor persistence of depressive symptoms was significantly associated with maintenance of glycemic control. Nevertheless, depressive symptoms...

journal_title：Diabetes research and clinical practice

authors： Van Buren DJ,Wilfley DE,Marcus MD,Anderson B,Abramson NW,Berkowitz R,Ievers-Landis C,Trief P,Yasuda P,Hirst K,TODAY Study Group.

更新日期：2018-01-01 00:00:00

abstract：AIMS:We investigated leukocyte relative telomere length (TL) in patients with type 2 diabetes (T2D) diagnosed for no longer than five years and its association with clinical and biochemical variables. METHODS:Peripheral blood leukocyte relative TL was investigated in 108 patients with T2D (87 women, 21 men) and 125 (3...

journal_title：Diabetes research and clinical practice

authors： Rosa ECCC,Dos Santos RRC,Fernandes LFA,Neves FAR,Coelho MS,Amato AA

更新日期：2018-01-01 00:00:00

abstract：AIMS:To investigate glycemic variability (GV) in Obstructive Sleep Apnea Syndrome (OSAS) patients by monitoring continuous blood glucose profile. METHODS:OSAS group (n=86) and normal control group (n=40) were included. Continuous blood glucose was monitored. The relationship of GV, insulin resistance index (IRI) and t...

journal_title：Diabetes research and clinical practice

authors： Peng CS,Cao YA,Tian YH,Zhang WL,Xia J,Yang L

更新日期：2017-12-01 00:00:00

abstract：AIMS:To test the accuracy of Diabetes Alert Dogs (DADs) by comparing recorded alerts to continuous glucose monitoring (CGM) device readings during waking and sleeping hours. METHODS:14 individuals (7 adults with type 1 diabetes and 7 youth with type 1 diabetes/parents) who owned DADs for ≥6 mos wore masked CGM devices...

journal_title：Diabetes research and clinical practice

authors： Gonder-Frederick LA,Grabman JH,Shepard JA

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Islet autoimmunity, age at onset and time to insulin treatment are often used to define subgroups of diabetes. However, the latter criterion is not clinical useful. Here, we examined whether an unbiased stratification of diabetes according to age at onset, fasting C-peptide and GAD autoantibodies (GADab) defi...

journal_title：Diabetes research and clinical practice

authors： Wod M,Yderstræde KB,Halekoh U,Beck-Nielsen H,Højlund K

更新日期：2017-12-01 00:00:00

abstract：AIMS:This study is amid at investigating the associations, and interactions of serum lipid biomarkers with microvascular complications of type 2 diabetes (T2D). METHODS:A nested case-control study was conducted within an ongoing prospective study on patients with T2D. Microvascular complications of T2D including diabe...

journal_title：Diabetes research and clinical practice

authors： Aryan Z,Afarideh M,Ghajar A,Esteghamati S,Esteghamati A,Nakhjavani M

更新日期：2017-11-01 00:00:00

abstract：AIMS:Insulin resistance (IR) detection is challenging and no test is currently used in clinical practice. We developed salivary biomarkers that could be used for IR detection. METHODS:We collected saliva from 186 healthy and 276 pre-diabetic participants, divided them into high and low IR groups based on a HOMA cutoff...

journal_title：Diabetes research and clinical practice

authors： Zhang Y,Sun J,Li F,Grogan TR,Vergara JL,Luan Q,Park MS,Chia D,Elashoff D,Joshipura KJ,Wong DTW

更新日期：2017-10-01 00:00:00

abstract：AIMS:Screening for depression is recommended internationally. The World Health Organization's 5-item Well-being Index (WHO-5) is used clinically to screen for depression but its empirical suitability for this purpose is not well documented. We investigated the psychometric properties of the WHO-5 and its suitability fo...

journal_title：Diabetes research and clinical practice

authors： Halliday JA,Hendrieckx C,Busija L,Browne JL,Nefs G,Pouwer F,Speight J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:To assess the usability and clinical effectiveness of diabetes mobile applications (diabetes apps) developed for adults with type 2 diabetes. METHOD:A systematic review of the usability and effectiveness of diabetes apps was conducted. Searches were performed using MEDLINE, EMBASE, COMPENDEX, and IEEE XPLOR...

journal_title：Diabetes research and clinical practice

authors： Fu H,McMahon SK,Gross CR,Adam TJ,Wyman JF

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The objective of this systematic review was to assess available scientific data on the efficacy and safety of medicinal food plants for the treatment of impaired glucose tolerance. METHODS:We included randomized controlled trials (RCTs) with a minimum follow-up period of 6weeks. The diagnosis was determined...

journal_title：Diabetes research and clinical practice

authors： Demmers A,Korthout H,van Etten-Jamaludin FS,Kortekaas F,Maaskant JM

更新日期：2017-09-01 00:00:00

abstract：AIMS:Diabetes therapies that provide durable glycaemic control for people with type 2 diabetes mellitus (T2DM) are needed. We present efficacy results of albiglutide, a glucagon-like peptide-1 receptor agonist, in people with T2DM over a 3-year period. METHODS:Five of the 8 HARMONY phase 3 trials, comparing albiglutid...

journal_title：Diabetes research and clinical practice

authors： Home PD,Ahrén B,Reusch JEB,Rendell M,Weissman PN,Cirkel DT,Miller D,Ambery P,Carr MC,Nauck MA

更新日期：2017-09-01 00:00:00

abstract：AIMS:We evaluated whether glucose fluctuation (GF) causes vascular endothelial injury and affects glucometabolic factors during lengthy oral glucose tolerance test (OGTT). METHODS:We enrolled consecutive 116 patients with coronary artery disease (CAD) who were performed coronary angiography and 4-h OGTT. Blood samples...

journal_title：Diabetes research and clinical practice

authors： Murata M,Adachi H,Oshima S,Kurabayashi M

更新日期：2017-09-01 00:00:00

abstract：AIM:Early interventions in prediabetes can prevent or delay the incidence of type 2 diabetes mellitus (T2DM). The aim of this review was to assess the efficacy and safety of traditional Chinese patent medicine (TCPM) on the prevention of T2DM. METHODS:Seven electronic databases were searched to identify eligible trial...

journal_title：Diabetes research and clinical practice

authors： Pang B,Lian FM,Zhao XY,Zhao XM,Jin,Lin YQ,Zheng YJ,Ni Q,Tong XL

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) is one of the most common chronic health conditions in adolescents in the United States. Adherence to the recommended treatment regimen has been reported as a source of stress for adolescents. AIM:The purpose of this study was to examine the associations among general and diabetes-spec...

journal_title：Diabetes research and clinical practice

authors： Rechenberg K,Whittemore R,Holland M,Grey M

更新日期：2017-08-01 00:00:00

abstract：AIMS:To investigate the alteration pattern and physiologic state of islet-specific miR-7 in the serum of patients with type 2 diabetes mellitus (T2DM) and T2DM-associated microvascular complications (T2DMC) and to evaluate its clinical significance. METHODS:The levels of serum miR-7 were firstly examined and compared ...

journal_title：Diabetes research and clinical practice

authors： Wan S,Wang J,Wang J,Wu J,Song J,Zhang CY,Zhang C,Wang C,Wang JJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The impact of cardiovascular complications on health-related quality-of-life (HRQoL) in type 2 diabetes mellitus has not been clearly established. Using EQ5D utility data from SAVOR-TIMI 53, a large phase IV trial of saxagliptin versus placebo, we quantified the impact of cardiovascular and other major event...

journal_title：Diabetes research and clinical practice

authors： Briggs AH,Bhatt DL,Scirica BM,Raz I,Johnston KM,Szabo SM,Bergenheim K,Mukherjee J,Hirshberg B,Mosenzon O

更新日期：2017-08-01 00:00:00

abstract：:We present a boy with mild hyperglycemia detected during an upper respiratory infection. Novel splicing mutation in the intron 1 of the GCK gene (c.45+1G>A) was detected, and was subsequently confirmed in his father. This is the first case of genetically confirmed Macedonian family with MODY. ...

journal_title：Diabetes research and clinical practice

authors： Kocova M,Elblova L,Pruhova S,Lebl J,Dusatkova P

更新日期：2017-08-01 00:00:00

abstract：AIMS:Centrally administered insulin improves cognitive functions in patients with Alzheimer's disease; however, it remains unknown whether long-acting insulin analogs exert more pronounced effects than insulin. In the present study, we directly compared the effects of insulin and its analogs on neural functions in vitr...

journal_title：Diabetes research and clinical practice

authors： Tsuneki H,Yoshida H,Endo K,Mori N,Hosoh S,Tsuda M,Wada T,Sasaoka T

更新日期：2017-07-01 00:00:00

abstract：:Growth arrest specific 6 (Gas6), a vitamin K-dependent protein plays a significant role in the regulation of cellular homeostasis via binding with TAM-receptor tyrosine kinases. Several studies reported the role of Gas6 in cancer, glomerular injury, obesity, and inflammation, however, very little is known about its ro...

journal_title：Diabetes research and clinical practice

authors： Dihingia A,Kalita J,Manna P

更新日期：2017-06-01 00:00:00

abstract：AIMS:To study the influence of the quantity and the quality of carbohydrate consumption on glycemic control in early pregnancy among women with type 1 diabetes. METHODS:A retrospective study of 107 women with type 1 diabetes who completed 1-3days of diet recording before first antenatal visit, as a part of routine car...

journal_title：Diabetes research and clinical practice

authors： Ásbjörnsdóttir B,Akueson CE,Ronneby H,Rytter A,Andersen JR,Damm P,Mathiesen ER

更新日期：2017-05-01 00:00:00

abstract：AIMS:Although serum complement factor 3 (C3) is an acute phase reactant mainly synthesized in the liver, several recent studies have shown high C3 gene expression in adipose tissue (AT). However, the relationship between C3 and AT levels has not been fully clarified in type 2 diabetes mellitus (T2DM) patients. METHODS...

journal_title：Diabetes research and clinical practice

authors： Nishimura T,Itoh Y,Yamashita S,Koide K,Harada N,Yano Y,Ikeda N,Azuma K,Atsumi Y

更新日期：2017-05-01 00:00:00

abstract：AIMS:Previously we revealed the effectiveness of a new therapeutic approach with a short-term, very-low dose fluvastatin-valsartan combination on the improvement of arterial function in type 1 diabetes mellitus patients (T1DM). In this study we explored whether this approach influences inflammation and oxidative stress...

journal_title：Diabetes research and clinical practice

authors： Lunder M,Janić M,Savić V,Janež A,Kanc K,Šabovič M

更新日期：2017-05-01 00:00:00

abstract：AIMS:Dipeptidyl peptidase-4 inhibitor (DPP-4i) is commonly used worldwide for the treatment of type 2 diabetes mellitus. In addition to its hypoglycemic activity, DPP-4i might have anti-inflammatory effects. In this study we examined the effects of DPP-4i on the serum levels of soluble CD163 (sCD163), a marker for acti...

journal_title：Diabetes research and clinical practice

authors： Hattori A,Takemoto M,Tokuyama H,Koshizaka M,Yokote K

更新日期：2017-04-01 00:00:00

abstract：AIMS:Deleterious effects of metabolic syndrome (MS) on bone are still controversial. In this study we evaluated the effects of a fructose-induced MS, and/or an oral treatment with metformin on the osteogenic potential of bone marrow mesenchymal stromal cells (MSC), as well as on bone formation and architecture. METHOD...

journal_title：Diabetes research and clinical practice

authors： Felice JI,Schurman L,McCarthy AD,Sedlinsky C,Aguirre JI,Cortizo AM

更新日期：2017-04-01 00:00:00

abstract：AIMS:The effects of travel distance and travel time to the primary diabetes care provider and waiting time in the practice on health-related quality of life (HRQoL) of patients with type 2 diabetes are investigated. RESEARCH DESIGN AND METHODS:Survey data of 1313 persons with type 2 diabetes from six regions in Englan...

journal_title：Diabetes research and clinical practice

authors： Konerding U,Bowen T,Elkhuizen SG,Faubel R,Forte P,Karampli E,Mahdavi M,Malmström T,Pavi E,Torkki P

更新日期：2017-04-01 00:00:00

abstract：AIMS:The aims were to assess effect of a short training programme on non-communicable diseases (NCDs), particularly diabetes on school teachers and also on students who were in turn educated by them. Lifestyle changes made by both groups were assessed 6months later. METHODS:Graduate teachers (n=1017) from 2 districts ...

journal_title：Diabetes research and clinical practice

authors： Selvam S,Murugesan N,Snehalatha C,Nanditha A,Raghavan A,Simon M,Susairaj P,Ramachandran A

更新日期：2017-03-01 00:00:00

abstract：AIM:To assess efficacy/safety of initial linagliptin/metformin single-pill combination (SPC) therapies versus individual drug components over 24weeks in treatment-naïve Asian patients with type 2 diabetes mellitus and insufficient glycemic control. METHODS:Patients (initial glycated hemoglobin [HbA1c] ⩾7.5% to <11.0% ...

journal_title：Diabetes research and clinical practice

authors： Mu Y,Pan C,Fan B,Hehnke U,Zhang X,Zhang X,Wang X,Liu J,Zhang Y,Du J,Ma J,Gong Y

更新日期：2017-02-01 00:00:00

abstract：AIMS:Amounts of macrophages were infiltrated in glomeruli in diabetic nephropathy. Heparanase has been thought to be closely related to proteinuria. Our aims were to determine the effect of heparanase on the inflammation in AGEs-stimulated macrophages and its role on the functions of glomerular endothelial cells (GEnCs...

journal_title：Diabetes research and clinical practice

authors： Xu G,Qin Q,Yang M,Qiao Z,Gu Y,Niu J

更新日期：2017-02-01 00:00:00

abstract：AIM:To identify characteristics of suboptimally controlled patients with type 2 diabetes (T2DM) on basal insulin treatment who may benefit from intensive titration or further intensification of treatment. METHODS:A post hoc analysis of SOLVE: a 24-week, international, observational study conducted in 17,374 patients w...

journal_title：Diabetes research and clinical practice

authors： Khunti K,Damci T,Husemoen LL,Babu V,Liebl A

更新日期：2017-01-01 00:00:00

abstract：AIMS:To investigate the association between nonadherence to diabetes treatment and the occurrence of diabetes complications. METHODS:Our study retrospectively identified adherence and nonadherence to diabetes treatment in patients during the first year of observation after new diagnoses of type 2 diabetes enrolled in ...

journal_title：Diabetes research and clinical practice

authors： Fukuda H,Mizobe M

更新日期：2017-01-01 00:00:00

abstract：AIMS:The present study aimed to evaluate effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4I), on cognitive functions in elderly diabetic patients with and without cognitive impairment. METHODS:253 elderly patients with type 2DM, were enrolled in this prospective and observational study. After comprehens...

journal_title：Diabetes research and clinical practice

authors： Isik AT,Soysal P,Yay A,Usarel C

更新日期：2017-01-01 00:00:00

abstract：AIM:Oxytocin regulates food intake, carbohydrate and lipid metabolism, and urinary sodium excretion. We assessed the association between serum oxytocin levels and presence of metabolic syndrome (MetS) in older men. METHODS:Cross-sectional study was performed in 540 volunteer men aged 50-85yrs from the MINOS cohort. Ox...

journal_title：Diabetes research and clinical practice

authors： Szulc P,Amri EZ,Varennes A,Panaia-Ferrari P,Fontas E,Goudable J,Chapurlat R,Breuil V

更新日期：2016-12-01 00:00:00